The synthesis and reactivity of imidazo[1,2‐a][1,8]naphthyridines are reported. Electrophilic substitution reactions were studied and the site of the reaction was established with the aid of high‐field 1H and 13C nmr spectra. The experimental C‐1 position reaction was correlated with a CNDO/2 calculations.
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Gueiffier et al. (1997) studied this question.
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