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Background/Objectives: The reliability of widely accessible multimodal artificial intelligence systems for rare or complex cutaneous vascular anomalies is uncertain. We evaluated diagnostic concordance and expert-rated management outputs across clinical-summary text, clinical-summary text plus images, and image-only workflows. Methods: In this cross-sectional audit, a purposively assembled, nonconsecutive challenge set of 511 published cases was evaluated with nine consumer web systems in new-conversation first-response sessions (13,797 final score records). Outputs were classified as top-1 concordance with the source-reported diagnosis, differential-list-only inclusion, or omission. Two vascular-anomaly specialists independently rated expected management appropriateness and safety on 5-point scales. Paired comparisons used exact McNemar, Friedman, and paired Wilcoxon tests. Results: Image-only top-1 concordance ranged from 0.4% to 7.0%, with omission rates of 71.0% to 97.8%; corresponding clinical-summary-text ranges were 32.9% to 53.0% and 11.5% to 29.4%. Image-only performance was lower than both text-containing workflows for every system. Text-plus-image workflows were not consistently superior to text alone. Conclusions: These date-stamped workflow contrasts do not estimate real-world diagnostic accuracy or isolate the causal contribution of images. They support preservation of clinical context and specialist oversight.
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Wang et al. (2026) studied this question.
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