The place of migraine as a channelopathy

Over the past 8 years an increasing awareness of the role of mutant ion channels in episodic diseases of humans has emerged. The importance of these discoveries is now being extended to a growing list of membrane excitability disorders of the nervous system. Molecular characterization of episodic diseases that are rare and monogenic will ultimately shed light on more common and complex disorders, such as epilepsy and migraine.