Key result
LV radial myocardial motion velocity gradients are significantly reduced in HCM and hypertensive LVH.
Why the study?
Assessment of regional myocardial function using radial myocardial motion velocity gradients measured by omni-directional M-mode echocardiography was needed to evaluate left ventricular function in patients with thickened myocardium.
Does omni-directional M-mode echocardiography improve the evaluation of regional myocardial function in patients with thickened myocardium?
Cross-Sectional (n=88)
Does omni-directional M-mode echocardiography improve the evaluation of regional myocardial function in patients with thickened myocardium?
p-value: p=<0.05
Omni-directional M-mode echocardiography can effectively detect reduced left ventricular radial myocardial motion velocity gradients in patients with hypertrophic cardiomyopathy and hypertensive left ventricular hypertrophy.
May aid regional function assessment in thickened LV; hypothesis-generating, requires prospective validation before clinical use.
To assess regional myocardial function with radial myocardial motion velocity gradients (MVGs) of the left ventricle measured by omni-directional M-mode echocardiography (OME). Thirty-two patients with hypertrophic cardiomyopathy (HCM), 20 patients with hypertension and left ventricular hypertrophy (HLVH), and 36 healthy volunteers (control group) were included in the study. The MVG of 16 segments on the left ventricular short axes of all subjects were measured and calculated using OME. In the control group, the MVG on left ventricular short axes were found to be decreased progressively from the base plane to the apical plane. Compared with the control group, the left ventricular MVGs were reduced in both the HCM group and the HLVH group (p < 0.05). The left ventricular MVG directly corresponded to regionally thickened myocardial motion. OME can be used as a tool to evaluate left ventricular myocardial function in patients with thickened myocardium and can have a significant role in clinical applications.
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Guo et al. (2013) conducted a cross-sectional in Hypertrophic cardiomyopathy and hypertensive left ventricular hypertrophy (n=88). Hypertrophic cardiomyopathy and hypertensive left ventricular hypertrophy vs. Healthy volunteers was evaluated on Left ventricular radial myocardial motion velocity gradients (MVGs) (p=<0.05). Left ventricular radial myocardial motion velocity gradients measured by omni-directional M-mode echocardiography were reduced in patients with HCM and HLVH compared to healthy controls (p<0.05).
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