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March 5, 2008Natural Product Research

Novel class of hybrid natural products derived from lupeol as antimalarial agents

Satish Kumar Namita Misra Kanwal Raj Kumkum Srivastava S.K. Puri

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Abstract

Thirty-four novel hybrid lupeol derivatives (4-18) were prepared and evaluated for antimalarial activity in vitro against Plasmodium falciparum. Three compounds (13d, 16a and 17a) have shown antimalarial activity at lower dose (10 microg mL(-1)) than lupeol.

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Kumar et al. (2008) studied this question.

synapsesocial.com/papers/6ab9d7d0cd7f4d39f6c375ca https://doi.org/10.1080/14786410701766349

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