Key result
Fat-suppressed CMR reliably provides noninvasive tissue diagnosis of intracardiac lipoma.
Why the study?
Noninvasive tissue diagnosis of intracardiac masses such as lipoma using magnetic resonance imaging techniques was demonstrated in this case.
Case Report (n=1)
Cardiac MRI with inversion-recovery fat suppression can noninvasively establish the tissue diagnosis of an intracardiac lipoma.
Supports noninvasive intracardiac lipoma diagnosis by fat-suppressed inversion-recovery MRI; leaves open prospective validation before wider adoption.
A 42-year-old male presented for evaluation of palpita- tions and chest pain.Physical examination suggested mild mitral regurgitation.Initial echocardiography showed a large mass attached to the interatrial septum.He then underwent cardiac magnetic resonance imaging for tissue characterization of the mass.Spin-echo imaging without (Figure , A) and with (Figure , B) inversion-recovery fat suppression showed a large intracardiac mass (arrow) that practically disappeared with fat suppression.The change in fat signal could also be appreciated by comparing the appearance of chest wall fat (arrowhead) by the 2 techniques.The diagnosis of lipoma was confirmed by histopathologic examination of the surgically excised mass (Figure , C and D).Because hydrogen protons in fat have a shorter T1 relaxation time than that of protons in most other tissues, inversion-recovery magnetic resonance imaging is uniquely able to suppress fat signal and establish a tissue diagnosis noninvasively in cases of lipoma.
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Raman et al. (2007) conducted a case report in Intracardiac mass (lipoma) (n=1). Cardiac magnetic resonance imaging with inversion-recovery fat suppression vs. Imaging without fat suppression was evaluated on Tissue diagnosis of lipoma. Inversion-recovery magnetic resonance imaging with fat suppression successfully established the noninvasive tissue diagnosis of an intracardiac lipoma.
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