Key result
Plexogenic arteriopathy drives fatal right heart failure in inactive systemic lupus erythematosus.
Why the study?
Pulmonary vasculitis associated with plexogenic arteriopathy in inactive systemic lupus erythematosus is not well characterized.
This case report describes the presence of plexogenic arteriopathy and pulmonary vasculitis in a patient with inactive SLE and pulmonary arterial hypertension.
May warrant PAH vigilance in inactive SLE; leaves open plexogenic arteriopathy as a mechanism independent of active disease.
Pulmonary arterial hypertension and compulmonale were found in a woman with inactive systemic lupus erythematosus (SLE). The patient died of right heart failure 5 years later. Postmortem study showed SLE reparative lesions, plexogenic arteriopathy and vasculitis in the lung vessels. Since no active SLE was found, the pulmonary vasculitis was attributed to plexogenic arteriopathy.
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Roncoroni et al. (2009) studied this question. Plexogenic arteriopathy was identified as the cause of pulmonary vasculitis and fatal right heart failure in a patient with inactive systemic lupus erythematosus.
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