Key result
Rotational atherectomy with DES achieves ~98% procedural success in complex coronary lesions.
Why the study?
The safety and effectiveness of rotational atherectomy followed by DES implantation in patients with complex coronary lesions required evaluation.
Is rotational atherectomy followed by DES implantation safe and effective in patients with complex coronary lesions?
Cohort (n=253)
No
Is rotational atherectomy followed by DES implantation safe and effective in patients with complex coronary lesions?
Rotational atherectomy followed by DES implantation is a safe and effective strategy for managing complex, calcified coronary lesions with a high procedural success rate and low long-term complication rates.
Answers are grounded in this paper and cite their sources.
May support use in select complex lesions; leaves open confirmation in randomized trials.
OBJECTIVE: To evaluate the safety and effectiveness of rotational atherectomy followed by drug eluting stent (DES) implantation in patients with complex coronary lesions. METHODS: From August 2006 to August 2012, 253 consecutive patients with 289 lesions and who underwent rotational atherectomy in our center were enrolled in this study. RESULTS: The overall procedure success rate was 98% with the cost of two (0.8%) coronary perforations, three (1.2%) dissections, five (2.0%) slow flows or no flows, three (1.2%) peri-procedure myocardial infarctions, and two (0.8%) in hospital deaths. During follow-up (mean three years), one (0.4%) patient died, two (0.8%) patients had acute myocardial infarction, 14 (5.5%) had restenosis, and target lesion revascularization occurred in eight patients (3.2%). CONCLUSIONS: Rotational atherectomy followed by DES implantation is a safe and effective technique for patients with complex coronary lesions, especially calcified and non-dilatable lesions.
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Jiang et al. (2012) conducted a cohort in complex coronary lesions (n=253). Rotational atherectomy followed by drug eluting stent (DES) implantation was evaluated on overall procedure success rate. Rotational atherectomy with DES implantation achieved a 98% procedure success rate in complex coronary lesions, with 0.8% in-hospital mortality and 3.2% target lesion revascularization at 3 years.
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