Key result
Enhanced MRI revealed a large central hematoma and inhomogeneous peripheral enhancement, leading to the diagnosis and surgical resection of breast angiosarcoma in a pregnant woman.
Case Report (n=1)
Clinicians should recognize the association of breast angiosarcoma with Kasabach-Merritt Syndrome using enhanced MRI to guide surgical approach.
MRI features may aid angiosarcoma diagnosis in pregnancy; this case report leaves open the need for validation before wider use.
INTRODUCTION: Primary breast angiosarcoma with spontaneous intratumoral bleeding associating with Kasabach-Merritt Syndrome is rarely reported. CASE FINDINGS/PATIENT CONCERNS: We herein present such a case in a 30-year-old pregnant woman who was initially diagnosed to hemangioma at her early gestation. However, the sudden rapid tumor growth was aware of the attention and intended for receiving the breast enhanced magnetic resonance imaging. DIAGNOSES AND INTERVENTIONS: The dynamic MRI enhancement showed inhomogenous enhancement at the periphery of the lobulated tumor on both early and delayed scans, otherwise a large hematoma was revealed at the center. Surgical resection was performed after baby delivery by Caeserean section, and histopathologic study confirmed breast angiosarcoma. CONCLUSION: Despite its rarity, clinicians should recognize the association of breast angiosacroma with Kasabach-Merritt Syndrome with suggestive finding of enhanced MRI in order to decide the surgical approach.
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Lin et al. (2016) conducted a case report in Primary breast angiosarcoma associated with Kasabach-Merritt Syndrome (n=1). Enhanced magnetic resonance imaging and surgical resection was evaluated on Diagnosis and surgical outcome. Enhanced MRI revealed a large central hematoma and inhomogeneous peripheral enhancement, leading to the diagnosis and surgical resection of breast angiosarcoma in a pregnant woman.
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