Several health related quality of life (HRQOL) instruments have been developed and used in HIV/AIDS research. Selecting an accurate instrument to evaluate how the HRQOL of persons living with HIV/AIDS evolve under care is essential. Accuracy is estimated with statistical methods that determine how HRQOL instruments perform internally and when compared to other measures. We review here the accuracy of measures used in fourteen HIV/AIDS HRQOL instruments. Some dimensions of accuracy have been measured in each of the instruments including construct validity, criterion validity, internal consistency reliability, sensitivity to change, and test-retest reliability, although none of these were evaluated using all measures of accuracy. There is a need for standardization of the statistical methods used to validate HRQOL in HIV/AIDS questionnaires and for an agreement on a standard instrument.
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Carabin et al. (2008) studied this question.
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