Adrenocortical Carcinoma in a 2 Years Old Girl, a Rare Cause of Clitoridomegaly: A Case Report

Background: Adrenocortical carcinoma (ACC) in childhood represent about 0.2% of all pediatric malignancies.Children had a higher incidence of virilization in 72% as common presenting symptom.The prognosis in children who have ACC appears to be better than that of adults, at least for early stage disease.The aim of this study was to evaluate the case of child with a low grade of ACC and to confirm the role of the margins free resection in ACC prognostic factors. Case Presentation:We present a 2 year old girl with progressive virilization since the neonates' period.The symptoms were including deepening of the voice, clitoromegaly, growth acceleration and premature pubic hair development associated with the low cortisolemy and hyper androgenemy.Abdominal CT scan concluded to the right adrenal tumor mass.She got the complete excision of 150 g of the mass.The histology concluded to ACC grade 2. Patient had an uneventful at 10 months postoperatively. Conclusion: ACC is rare in children.Only complete surgical excision is sufficient in the case of low grade of ACC in pediatric population.Clinical examination, hormonal and imaging follow up remain necessary to any recurrence.