Key result
Takotsubo cardiomyopathy triggers marked, reversible QTc prolongation and concordant T-wave inversions during RV apical pacing.
Why the study?
ECG manifestations in Takotsubo cardiomyopathy have not been well characterized in patients with right ventricular apical pacing.
Case Report (n=1)
Significant QTc prolongation and concordant T-wave inversions can be observed in Takotsubo cardiomyopathy even during full right ventricular apical pacing.
Marked QTc prolongation may occur with RVA pacing in Takotsubo; case report leaves open prevalence and risk stratification.
In Takotsubo cardiomyopathy (TCM), ST‐segment elevation, T‐wave inversion, and QTc prolongation are the most common electrocardiography (ECG) findings during acute and subacute periods. Right ventricular apical (RVA) pacing produces a left ventricular electrical activation sequence resembling a left bundle‐branch block, and the ST–T segment changes are usually discordant from the QRS complex. Several cases have reported that abnormal ECG manifestations in TCM could be detected even in patients with a paced ventricular rhythm. However, ECG manifestations in TCM have not been well characterized in patients with RVA pacing. Here, we report a case of a 76‐year‐old woman with RVA pacing who was diagnosed with TCM after she experienced acute bronchitis. To the best of our knowledge, this is a rare case, showing that significant QTc prolongation and concordant T‐wave inversions during full RVA pacing were longer and deeper when compared with ECG findings in past reports. The ECG findings eventually improved with a similar course as those in TCM patients without RVA pacing.
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Matsumoto et al. (2014) conducted a case report in Takotsubo cardiomyopathy with right ventricular apical pacing (n=1). Right ventricular apical pacing was evaluated on Electrocardiography (ECG) manifestations. A 76-year-old woman with right ventricular apical pacing and Takotsubo cardiomyopathy exhibited significant QTc prolongation and concordant T-wave inversions that eventually improved.
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