Management of Antiplatelet and Anticoagulation Therapy in Patients Undergoing Elective Craniotomy: A Delphi-Based Swiss National Consensus

Q: What is the clinical evidence from this study?

Study design: Observational. Population: Intracranial meningiomas. Intervention: Radical surgical intervention (extent of resection). Primary outcome: Early clinical outcomes, rate of reoperations, and intrahospital mortality.

Q: What does this research mean for the field?

Early clinical success and reduced reoperation rates following surgical treatment of intracranial meningiomas depend significantly on the extent of resection and patient condition upon admission, while histopathological grade does not affect intrahospital mortality. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Tabea Stössel; Lukas Andereggen; Fabian Baumann; Menno Germans; Raphael Guzman; Serge Marbacher; Mahmoud Messerer; Davide Milani; Manuel Moser; Gerrit Schubert; Carlo Serra; Christian Zweifel; Jehuda Soleman

doi:10.1016/j.bas.2026.107388

January 1, 2026Brain and SpineOpen Access

Management of Antiplatelet and Anticoagulation Therapy in Patients Undergoing Elective Craniotomy: A Delphi-Based Swiss National Consensus

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Why the study?

Does a more radical surgical intervention improve early clinical outcomes and reduce reoperations in patients with intracranial meningiomas?

Key Points

Determine the impact of resection extent, patient admission status, and tumor grade on early clinical outcomes and mortality following craniotomy for intracranial meningiomas.
Evaluated clinical and surgical parameters in patients undergoing elective craniotomy for intracranial meningioma resection.
Analyzed associations between patient age (t = -2.73, p = 0.21), admission condition, histopathological grade, and postoperative outcomes.
Early clinical success depended significantly on admission condition and the extent of surgical resection.
Radical surgical intervention markedly reduced the rate of repeat operations.
Histopathological grade did not affect intrahospital mortality.

Study Design

Type

Observational

Structured PICO

Does a more radical surgical intervention improve early clinical outcomes and reduce reoperations in patients with intracranial meningiomas?

P

Population

Patients undergoing surgical treatment of intracranial meningiomas (based on abstract) or elective craniotomy (based on title)

E

Exposure

Radical surgical intervention (extent of resection)

O

Outcome

Early clinical outcomes, rate of reoperations, and intrahospital mortalityhard clinical

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Implication

In patients undergoing surgical treatment for intracranial meningiomas, a more radical resection reduces the rate of reoperations without histopathological grade affecting intrahospital mortality.

Abstract

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Discussion

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Cite This Study

Stössel et al. (2026) conducted an observational in Intracranial meningiomas. Radical surgical intervention (extent of resection) was evaluated on Early clinical outcomes, rate of reoperations, and intrahospital mortality.

synapsesocial.com/papers/6abc576efbfca106a1247e65 https://doi.org/10.1016/j.bas.2026.107388

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Management of Antiplatelet and Anticoagulation Therapy in Patients Undergoing Elective Craniotomy: A Delphi-Based Swiss National Consensus

Key Points

Study Design

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Management of Antiplatelet and Anticoagulation Therapy in Patients Undergoing Elective Craniotomy: A Delphi-Based Swiss National Consensus

Key Points

Study Design

Structured PICO

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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