1 The effects of methyldopa withdrawal on liver function and drug metabolism were investigated in ten elderly females suffering from the drug-induced orthostatic reaction and resistant hypertension. 2 There was a significant increase in serum albumin level, antipyrine metabolism and urinary excretion of D-glucaric acid 6 months after the methyldopa withdrawal. 3 The results suggest that patients treated with methyldopa might show a reduced metabolizing ability in spite of normal liver function tests.
No takes yet. Share an insight, caveat, or question.
Ylikallio et al. (1980) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: