Key result
Complications drive TEVAR indications in uncomplicated type B aortic dissection for ~86% of surveyed investigators.
Why the study?
Uncertainty remains regarding indications for intervention and treatment strategies of TEVAR in uncomplicated type B aortic dissection among experts.
Cross-Sectional (n=43)
Yes
There is broad agreement on TEVAR indications for complicated TBAD but significant variation in interpreting high-risk imaging features and procedural strategies for uncomplicated TBAD among SUNDAY network PIs, highlighting the need for prospective evidence.
Captured external expert commentary on this paper, strongest first. Original sources are linked where available.
“Being a strategy-based trial (like the IMPROVE trial for ruptured abdominal aortic aneurysm [AAA]) it is important that investigator truly attempt to include and randomise patients before evaluating the applicability of a TEVAR procedure or the trial might be biased towards 'cherry picking' only anatomically appealing candidates which might skew the trial in favour of TEVAR.”
Supports consensus on TEVAR for complicated TBAD; leaves open standardization of criteria for uncomplicated cases and high-risk features.
Background: Thoracic endovascular aortic repair (TEVAR) is increasingly considered in selected patients with uncomplicated type B aortic dissection (uTBAD), but uncertainty remains regarding indications for intervention and treatment strategies. This study aimed to explore potential variation in TEVAR indications and treatment strategies for uTBAD among principal investigators (PIs) of the Scandinavian trial of Uncomplicated Aortic Dissection Therapy (SUNDAY). Methods: A prospective, cross-sectional, questionnaire-based study was conducted among PIs of the SUNDAY trial network. A structured survey was developed by the first and last author using contemporary guidelines and relevant literature and was subsequently reviewed by all co-authors. The questionnaire addressed three topics: definitions, TEVAR indications, and treatment strategies. Data were collected via Castor and analyzed using SPSS version 29.0. A center-weighted sensitivity analysis and within-center concordance analysis were performed to account for multiple respondents from the same center. Results: The response rate was 78.2% (43/55 PIs), representing 31 centers. The presence or development of complications was the main driver for TEVAR (37/43, 86.0%). Rupture (43/43, 100%), clinical signs of malperfusion (43/43, 100%), and rapid aortic expansion (38/43, 88.4%) were consistently considered indications for TEVAR, whereas more variation was observed for refractory pain (28/43, 65.1%) and refractory hypertension (26/43, 60.5%). Interpretation of high-risk imaging features varied, with 37.2% (16/43) considering multiple features an indication for TEVAR. Procedural strategies varied, with spot stenting selected by 58.1% (25/43) of respondents, although more extensive aortic coverage was also reported. Landing zone characteristics and oversizing preferences were more consistent, with 79.1% (34/43) defining a healthy landing zone by the absence of intramural hematoma or dissection, 58.1% (25/43) preferring a landing zone length of 2 cm, and 51.2% (22/43) preferring 10% stent graft oversizing. Center-weighted sensitivity analyses showed generally similar estimates, whereas within-center concordance varied across items (range 20–100%), with complete agreement for 8 of 50 items. Conclusions: Among SUNDAY PIs, there was broad agreement regarding the distinction between uncomplicated and complicated type B aortic dissection (TBAD) and the role of TEVAR in the presence of complications, whereas variation remained in the interpretation of high-risk imaging features and procedural strategies. These findings highlight variation in decision-making regarding the management of uTBAD within the SUNDAY network and support the need for prospective evidence to guide TEVAR decision-making.
No takes yet. Share an insight, caveat, or question.
Biersteker et al. (2026) conducted a cross-sectional in Uncomplicated type B aortic dissection (n=43). Survey on TEVAR indications and treatment strategies was evaluated on Variation in TEVAR indications and treatment strategies. Among surveyed principal investigators, 86.0% considered the presence or development of complications as the main driver for TEVAR in uncomplicated type B aortic dissection.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: