Key result
Amiodarone reduces postoperative atrial fibrillation, an event occurring in ~35% of valve surgeries.
Why the study?
Postoperative atrial fibrillation is a common complication after cardiac surgery with increasing incidence and associated risk factors and complications that require further examination.
Does amiodarone prevent postoperative atrial fibrillation in patients undergoing cardiac surgery?
Does amiodarone prevent postoperative atrial fibrillation in patients undergoing cardiac surgery?
Postoperative atrial fibrillation is a highly prevalent complication after cardiac surgery, occurring in 30% to 40% of patients after valve replacement or repair.
Answers are grounded in this paper and cite their sources.
Persistent POAF burden after valve surgery highlights prophylaxis gaps; extends evidence base for novel prevention approaches.
In Brief Atrial fibrillation is the most common complication occurring after coronary artery bypass graft surgery. The purpose of this article was to examine the incidence of, risk factors related to, and complications caused by postoperative atrial fibrillation. The pathophysiology and treatment of atrial fibrillation and postoperative atrial fibrillation will also be discussed. The incidence of postoperative atrial fibrillation after isolated coronary artery bypass surgery is 30% to 40% after valve replacement or repair and continues to increase. This article reviews meta-analyses of this topic.
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McAlister et al. (2011) conducted a review in Postoperative atrial fibrillation. Amiodarone was evaluated. This review examines meta-analyses on amiodarone use to prevent postoperative atrial fibrillation, noting an incidence of 30% to 40% after valve replacement or repair.
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