النشاط المضاد للبكتيريا للمستخلصات المائية الإيثانولية من ثمار السنط النيلي وقشور الرمان ضد الإشريكية القولونية والمكورات العنقودية الذهبية في ولاية الجزيرة، السودان

Plants as a source of medicinal compound have continued to play a vital role in the maintenance of human health since ancient times. The present study aimed to determine the antibacterial activities of Acacia nilotica fruit and Punica granatum peel against the local strains of E. coli and Staphylococcus aureus. The plant materials and the target microorganisms were brought from within Wad Medani City, Gezira State, Sudan. The standard methods of preparation of hydro-ethanol extracts, purifying and culturing microorganisms, and bioassay antibacterial activity tests were carefully followed. The results of this study revealed that, the lower concentration (1.14 mg/ml) of the hydro-ethanol extract of A. nilotica fruit produced a mean of 5.3+0.3 mm inhibition zone on E. coli, and 6.67+0.3 mm on S. aureus, whereas, the higher concentration (92.0 mg/ml) show inhibition zones of 12.67+0.67 mm on E. coli strain and 13.3+0.3 mm on S. aureus strain. The lower concentration (0.72 mg/ml) of the hydro-ethanol extract of pomegranate peel produced a mean of 6.7+0.67 mm inhibition zone on E. coli, and 6.7+0.67 mm on S. aureus, whereas, the higher concentration (89.32 mg/ml) show inhibition zones of 11.3+0.3 mm on E. coli strain and 12.0+0.0 mm on S. aureus strain. It was noticed that, S. aureus was relatively similar in its susceptible to E. coli strain against both plant extracts, but not against penicillin antibiotic. The study recommends running further studies that focuses on other local natural products within the study area, also on other pathogens.