Comparative Analysis of Minimally Invasive and Classical Approaches in the Surgical Treatment of Isolated Mitral Valve Insufficiency: Immediate Results and Functional Recovery of Patients

Q: What are the key findings of this study?

Right-sided minithoracotomy for mitral valve repair significantly reduced intraoperative blood loss (196.8 vs 273.1 ml, p<0.001) and shortened intensive care unit stay compared to median sternotomy.

Q: What is the clinical evidence from this study?

Study design: Cohort. Population: Isolated mitral valve insufficiency (n=134). Intervention: Right-sided minithoracotomy vs. Median sternotomy. Primary outcome: Intraoperative blood loss (ml) (p=<0.001).

Q: What does this research mean for the field?

Right-sided minithoracotomy for mitral valve repair significantly reduces intraoperative blood loss and shortens intensive care unit and hospital stay compared to median sternotomy. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.NEUTRAL.

Q: What question did this study set out to answer?

To compare clinical efficacy, safety, early postoperative outcomes, and functional recovery rates between right minithoracotomy and median sternotomy for mitral valve repair.

V. V. Fylypchuk; V. V. Lazoryshynets

doi:10.29254/2077-4214-2026-3-182-342-348

January 1, 2026Bulletin of Problems Biology and MedicineOpen Access

Comparative Analysis of Minimally Invasive and Classical Approaches in the Surgical Treatment of Isolated Mitral Valve Insufficiency: Immediate Results and Functional Recovery of Patients

View Full Paper

Ask AI

Bookmark

Share

Key result

Right minithoracotomy linked to ~28% lower intraoperative blood loss vs sternotomy in mitral repair.

P<0.001
n=134

Why the study?

The optimal surgical approach for isolated mitral valve insufficiency remains debated, with limited comprehensive data comparing minimally invasive and classical methods on immediate outcomes and functional recovery.

Does right minithoracotomy improve early postoperative outcomes and functional recovery compared to median sternotomy in patients with isolated mitral valve insufficiency?

Key Points

To compare clinical efficacy, safety, early postoperative outcomes, and functional recovery rates between right minithoracotomy and median sternotomy for mitral valve repair.
Retrospective cohort analysis of N=134 patients with isolated mitral valve insufficiency treated between 2020 and 2024 at a single cardiovascular center in Ukraine.
Patients underwent mitral valve repair via right minithoracotomy (n=59) or conventional median sternotomy (n=75).
Evaluated operative duration, cardiopulmonary bypass and aortic cross-clamp times, blood loss, intensive care unit stay, analgesia demand, and recovery speed.
Right minithoracotomy was associated with longer operative duration, cardiopulmonary bypass time, and aortic cross-clamping time, but significantly lower intraoperative blood loss compared to sternotomy.
The minithoracotomy group experienced shorter intensive care unit and hospital stays, reduced analgesic requirements, earlier mobilization, and faster resumption of physical and daily activities.
Duration of mechanical ventilation and postoperative complication rates did not differ statistically significantly between surgical approaches.

Study Design

Type

Cohort (n=134)

Multicenter

No

Structured PICO

Does right minithoracotomy improve early postoperative outcomes and functional recovery compared to median sternotomy in patients with isolated mitral valve insufficiency?

P

Population

134 patients with isolated mitral valve insufficiency who underwent surgical repair between 2020 and 2024, evaluated for immediate postoperative outcomes and functional recovery.

I

Intervention

Mitral valve repair via right minithoracotomy

C

Comparator

Mitral valve repair via traditional median longitudinal sternotomy

O

Outcome

Intraoperative blood loss, operation duration, cardiopulmonary bypass time, aortic cross-clamp time, mechanical ventilation duration, ICU stay, analgesia duration, hospital stay, functional recovery time, and postoperative complications

Main Result

Absolute Event Rate: 196.8% vs 273.1%

p-value: p=<0.001

Limitations

Single-center design
Relatively small number of patients
Retrospective design
single-center design
relatively small sample size

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

Right minithoracotomy for mitral valve repair reduces intraoperative blood loss, shortens ICU stay, and accelerates functional recovery compared to median sternotomy, despite longer operative times.

Abstract

Филипчук В. В

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Fylypchuk et al. (2026) conducted a cohort in Isolated mitral valve insufficiency (n=134). Right-sided minithoracotomy vs. Median sternotomy was evaluated on Intraoperative blood loss (ml) (p=<0.001). Right-sided minithoracotomy for mitral valve repair significantly reduced intraoperative blood loss (196.8 vs 273.1 ml, p<0.001) and shortened intensive care unit stay compared to median sternotomy.

synapsesocial.com/papers/6ac1abb2cc6172083c928af7 https://doi.org/10.29254/2077-4214-2026-3-182-342-348

View Full Paper

Ask AI

Bookmark

Share

Comparative Analysis of Minimally Invasive and Classical Approaches in the Surgical Treatment of Isolated Mitral Valve Insufficiency: Immediate Results and Functional Recovery of Patients

Key Points

Study Design

Structured PICO

Main Result

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Comparative Analysis of Minimally Invasive and Classical Approaches in the Surgical Treatment of Isolated Mitral Valve Insufficiency: Immediate Results and Functional Recovery of Patients

Key Points

Study Design

Structured PICO

Main Result

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading