Key result
Hypertension in heavy smokers is linked to ~32% higher WBC counts.
Why the study?
Tobacco smoking and hypertension both impact hematological parameters and may contribute to cardiovascular and organ damage, but the extent of adverse effects in hypertensive smokers compared to healthy smokers was not well defined.
Does the presence of hypertension alter hematological parameters in heavy smokers compared to healthy heavy smokers?
Cross-Sectional (n=210)
No
Does the presence of hypertension alter hematological parameters in heavy smokers compared to healthy heavy smokers?
The combination of hypertension and heavy smoking is associated with significant elevations in hematological parameters such as WBC, RBC, and hemoglobin compared to smoking alone, potentially increasing cardiovascular risk.
Answers are grounded in this paper and cite their sources.
Hypertensive smokers showed higher WBC and red cell indices; hypothesis-generating for CV risk and needs prospective validation.
Objective: Tobacco smoking considered as the main causes of death in the world which leading to both acute and may chronic impacts on hematological parameters. In addition, hypertension is one of the health problems of the world. It may lead to cause cardiovascular disease furthermore cause functional disturbances to hematological parameters. Subsequently, it may enhance an organ damage. The aim of our study was to estimate the extent of adverse impacts of tobacco smoking on biochemical characteristics in hypertension comparing with healthy smokers. Methods: Our study was conducted from October 2019 to January 2020 on a total of 110 smokers who have hypertension and 100 who are healthy smokers individuals at Baqubah Teaching Hospital. The smokers were regularly consuming 30-45 cigarettes per day for at least for 4years. The ethical guidelines constructed by the Scientific Committee of the Institute have been taken where the acceptance have also taken from volunteers. Blood samples have been collected via EDTA tubes 3ml of blood and tested by fully automatic hematological analyzer (DIAGON Ltd- D-Cell 60). Conclusion: Excessive smoking with hypertension existing causing abnormal and significantly increases of hematological parameters which is lead to early atherosclerosis, cardiovascular diseases, polycythemiavera and chronic obstructive pulmonary disease.
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Salman et al. (2020) conducted a cross-sectional in Hypertension in smokers (n=210). Hypertension vs. Healthy smokers was evaluated on White blood cell (WBC) count (x10^9/L) (p=0.001). Hypertension in heavy male smokers was associated with significantly increased white blood cell counts (8.25 vs 6.25 x10^9/L, p=0.001) and other elevated hematological parameters compared to healthy smokers.
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