Chloride locks the rings: Debenzylation of a chloride-templated N-benzyl pyridinium catenane, allows for a 180° “pirouetting” of the rings in the resulting neutral pyridyl catenane (see scheme). The catenane may be returned to its original co-conformation by chloride recognition as evidenced in solution and in the solid state.
No takes yet. Share an insight, caveat, or question.
Evans et al. (2011) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: