Key result
Experimental coronary thrombi demonstrate ongoing fibrinogen incorporation and growth for at least 72 hours.
Why the study?
The temporal growth dynamics and fibrinogen incorporation into coronary artery thrombi after initial formation were not well characterized.
p-value: p=<0.001
No takes yet. Share an insight, caveat, or question.
Experimental CA thrombus growth remains hypothesis-generating; leaves open relevance to human ACS and antithrombotic timing.
Oliver et al. (1977) studied Experimental coronary artery thrombi. 131I-fibrinogen vs. 131I-albumin was evaluated on Radioactivity measured in thrombi segments (p=<0.001). 131I-fibrinogen incorporation in experimental coronary artery thrombi was significantly greater than 131I-albumin (P<0.001), indicating continued thrombus growth for at least 72 hours.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: