Key result
Endotracheal intubation is linked to an immediate ~8% rise in systolic blood pressure.
Why the study?
Endotracheal intubation and laryngoscopy induce stress responses such as hypertension and tachycardia, but their impact on pulse rate and blood pressure during anesthesia requires assessment.
Does endotracheal intubation increase blood pressure and pulse rate in patients undergoing general anesthesia?
Observational (n=50)
Yes
Does endotracheal intubation increase blood pressure and pulse rate in patients undergoing general anesthesia?
Absolute Event Rate: 135.58% vs 124.98%
p-value: p=≤0.05
Endotracheal intubation induces a transient but significant sympathetic stress response, elevating blood pressure and heart rate.
Requires hemodynamic vigilance during intubation; extends sympathetic response data but leaves open outcome impact in observational cohorts.
Endotracheal intubation and laryngoscopy have become necessary to provide sufficient airway management, deliver anesthesia and avoid aspiration in anesthetized individuals. Laryngoscopy and intubation have been shown to induce a broad spectrum of stress responses e.g. hypertension and tachycardia. The current study aimed to assess the impact of endotracheal intubation on the pulse rate (P.R) and blood pressure (B.P) during different time intervals of general anesthesia. This study was performed in Baghdad teaching and Gazzi AL-Harriri hospitals during 2019-2020. A total of fifty (50) patients were included in the study; twenty-five (25) were females and twenty-five (25) males with American society of anesthesiologist (ASA) physical status (I & II). The ages of patients ranged between (16-60) years. All patients were administrated (I.V.) Dexamethasone (0.11 mg/kg), Metoclopramide (0.14mg/kg), Ranitidine (0.71mg/kg) & Ketamine (0.5 mg/kg) as premedication. At the induction of anesthesia, patients were administrated (2-3 mg/kg) Propofol as a hypnotic drug and succinylcholine 1 mg/kg as a muscle relaxant. The results revealed a significant increase (p≤0.05) in systolic/ diastolic blood pressure (B.p) at- intubation (135.58 ± 10.29 / 91.74 ± 10.91) and also at 1 minute (132.34 ± 10.08 / 88.58 ± 13.06 ). There was also a significant increase (p≤0.05) in pulse rate (P.R) at-intubation (103.00 ± 18.59).
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Azhar A. Mhaibes (2022) conducted an observational in Patients undergoing elective surgeries requiring general anesthesia and endotracheal intubation (n=50). Endotracheal intubation vs. Pre-induction baseline was evaluated on Systolic blood pressure at intubation (p=≤0.05). Endotracheal intubation significantly increased systolic and diastolic blood pressure as well as pulse rate immediately at intubation compared to pre-induction baseline.
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