Key result
Low-intensity resistance training with blood flow restriction improves paretic knee torque ~35% over traditional training.
Why the study?
Chronic ischemic stroke causes persistent paretic-limb weakness and impaired dynamic postural stability, limiting functional recovery, and optimal resistance training strategies are unclear.
Does Low-Intensity Resistance Training with Blood Flow Restriction improve isokinetic knee torque and dynamic postural stability in patients with chronic ischemic stroke compared to traditional high-load resistance training?
RCT (n=40)
Single-blind
1:1 ratio using a computer-generated randomization sequence
No
Does Low-Intensity Resistance Training with Blood Flow Restriction improve isokinetic knee torque and dynamic postural stability in patients with chronic ischemic stroke compared to traditional high-load resistance training?
Low-intensity resistance training with blood flow restriction produced significantly greater improvements in paretic-limb strength and dynamic postural stability than traditional high-load resistance training in patients with chronic ischemic stroke.
Supports low-intensity BFR over high-load RT for paretic knee strength in chronic stroke; extends BFR evidence to neurological rehabilitation.
Background: Chronic ischemic stroke frequently results in persistent paretic-limb weakness and impaired dynamic postural stability, limiting functional recovery. Objective: To compare the effects of Low-Intensity Resistance Training with Blood Flow Restriction (LIRT-BFR) versus traditional high-load resistance training on isokinetic knee torque and dynamic postural stability in chronic ischemic stroke. Methods: Forty patients with chronic ischemic stroke, their age ranged from 40 to 45 years old were randomly allocated to an LIRT-BFR study group (40% 1-RM with cuff inflation at 150–160 mmHg) and a traditional resistance-training control group (80% 1-RM, no cuff), each completing 5 weeks of supervised training, three sessions per week. Peak torque of paretic-side knee extension and flexion at 30°/s and 90°/s was measured using an IsoMed 2000 isokinetic dynamometer, and dynamic postural stability was assessed via the Overall Stability Index (OSI) using the Biodex Balance System. A 2×2 mixed-design MANOVA was used for between- and within-group comparisons. Results: Both groups showed significant pre-to-post improvements in all outcomes, however, the LIRT-BFR group demonstrated significantly greater gains than the traditional resistance-training group across all isokinetic torques and OSI (P<0.05). Conclusion: LIRT-BFR produced significantly greater improvements in paretic-limb isokinetic knee strength and dynamic postural stability than traditional high-load resistance training in patients with chronic ischemic stroke, supporting its use as an effective, lower-load rehabilitation strategy.
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Ella et al. (2025) conducted an RCT in Chronic ischemic stroke (n=40). Low-Intensity Resistance Training with Blood Flow Restriction (LIRT-BFR) vs. Traditional resistance training (80% 1-RM, no cuff, 3 sessions per week) was evaluated on Peak torque of paretic-side knee flexion at 30°/s (MD 7.68, 95% CI 5.48-9.89, p=0.0001). Low-intensity resistance training with blood flow restriction significantly improved paretic-side knee flexion peak torque at 30°/s compared to traditional resistance training (MD 7.68, p=0.0001).
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