Editor,—Craft1 is right to point out that steps to control selection bias by alternation or randomisation to treatment groups did not begin with the Dutch trials of paludrine in malaria and the Medical Research Council’s (MRC) first trial …
No takes yet. Share an insight, caveat, or question.
Iain Chalmers (1999) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: