Geometric Means, Reference Ranges, and Selected Percentile Points for Blood Volume Measurements by Age, Race/Ethnicity, and Gender

Background: Blood volume measurements provide important clinical parameters in certain treatment situations. Method: While a fast, accurate and reliable methodology has been available to estimate the blood volume measurements for almost a decade, the availability of “normal” or “should be” blood volume measurements have not been readily available. In this article, we have provided geometric means and selected percentiles points with 95% confidence intervals for total blood volume, red cell volume, and plasma volume for children aged 8-11 years old, adolescents 12-17 years old, and adults aged 18 years and over by gender, race/ethnicity, age, and body mass index. The reference ranges are also provided. Result: We have also provided mathematical formulae that can be used to compute “should be” blood measurements for specific patients with a given gender, race/ethnicity, age, and body mass index. Conclusion: It is up to individual physicians to decide in a given treatment situation which “should be” index, e.g., geometric mean vs. median they want to use for comparison with actual estimated blood measurements.