Key result
Amyl nitrite inhalation produces ischemic ECG changes similar to exercise testing in coronary sclerosis.
Why the study?
Amyl nitrite inhalation causes electrocardiographic changes indicating temporary coronary insufficiency in patients with sclerotic coronary vessels, suggesting a mechanism involving increased cardiac work and decreased blood supply leading to ischemia.
Population
Patients with sclerotic coronary vessels
Comparison
Amyl nitrite inhalation vs exercise test in the same patients
Design
Observational study
Authors
Loading...
May provoke ischemia on ECG in coronary disease; leaves open validation as diagnostic alternative to exercise testing.
Observational
Contro et al. (1952) conducted an observational in Coronary heart disease. Amyl nitrite inhalation vs. Exercise test was evaluated on Electrocardiographic changes typical of temporary coronary insufficiency. Amyl nitrite inhalation in patients with sclerotic coronary vessels induced electrocardiographic changes typical of temporary coronary insufficiency, yielding similar results to an exercise test.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: