Systemically comparing host immunity between survived and deceased COVID-19 patients

Novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the disastrous pandemic of Coronavirus Disease-2019 (COVID-19). 1 , 2 , 3 Although the epidemiological, clinical, and immunological characteristics of COVID-19 have been reported, 4 , 5 , 6 the kinetics of immune responses and their association with clinical outcomes remain poorly understood. Here, we summarize the characteristics of cellular immune responses in a total of 157 COVID-19 patients enrolled in Tongji Hospital between February and March 2020 and compare the properties between 95 survived and 62 deceased patients with different onset time. The demographic and clinical characteristics of these patients are shown in Supplementary Table 1 . No significant difference in age, gender, clinical symptoms, and imaging features was recorded between survived and deceased patients.