Flame burns are consistently associated with higher mortality than scald injuries; however, it remains unclear whether burn mechanism independently influences outcome or primarily reflects differences in injury severity. We performed a retrospective analysis of a prospectively maintained registry including 1,069 adult patients with flame or scald burns admitted to a tertiary burn intensive care unit between 2000 and 2024. The primary outcome was ICU mortality. Logistic regression analyses evaluated the association between burn mechanism and mortality before and after adjustment for ABSI and calendar year, with an additional model incorporating the individual ABSI components and calendar year. Patients with flame burns had significantly larger burns, higher ABSI scores, more frequent inhalation injury, and a higher prevalence of full-thickness burns (all p < 0.001). Crude ICU mortality was significantly higher following flame burns than scald injuries (27.8% vs. 10.3%; OR 3.36, 95% CI 2.26–5.01; p < 0.001). However, burn mechanism was no longer independently associated with mortality after adjustment for ABSI and calendar year (OR 1.03, 95% CI 0.63–1.69; p=0.913) or after adjustment for the individual ABSI components and calendar year (OR 0.99, 95% CI 0.57–1.71; p=0.967). Age, total body surface area burned, inhalation injury, and full-thickness burns remained independently associated with mortality. These findings indicate that the higher mortality observed after flame burns is explained by greater injury severity rather than burn mechanism itself. Burn mechanism should therefore be regarded primarily as a marker of injury severity rather than an independent predictor of ICU mortality, reinforcing the importance of validated severity scores for prognostic assessment.
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Christ et al. (2026) studied this question.
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