Key result
Adult TCPC is linked to impaired exercise capacity, with peak VO2 averaging ~20 ml/kg/min.
Why the study?
The clinical and psychological profile and determinants of quality of life after total cavopulmonary connection procedure in adults were not well characterized.
Observational (n=21)
Impaired exercise capacity after total cavopulmonary connection warrants monitoring; leaves open whether interventions can slow time-dependent decline.
Objective: The aim of this study was to evaluate the clinical and psychological profile of after total cavopulmonary connection procedure and to identify the significant determinants of quality of life. Methods: Data from 21 patients underwent total cavopulmonary connection procedure from January 2001 to December 2015 were retrospectively analyzed. Patients underwent an echocardiography and cardiopulmonary exercise testing. Used ST-36 questionnaire to perceived health status. The NT-pro BNP levels was test. Results: 21 patients aged between 19 to 36 years (mean 26.6 years) were enrolled. The mean follow-up time was 44.2 ± 29.9 months. The mean EF was 59.4 ± 6.2%, and the mean maximal oxygen consumption was 19.9 ± 3.6 ml/kg/min, predict value was 52.5 ± 8.9%. SF-36 score was well. Independent risk for impaired exercise capacity was interval time from surgery. Conclusions: The exercise capacity of total cavopulmonary connection patients was impaired. Identify more predict factors of the quality of these patients need further study.
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Xiaosng et al. (2017) conducted an observational in Total cavopulmonary connection (n=21). Total cavopulmonary connection was evaluated on Exercise capacity and quality of life. Adult patients who underwent total cavopulmonary connection had impaired exercise capacity (mean maximal oxygen consumption 19.9 ml/kg/min), with time from surgery as an independent risk factor.
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