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A 24-year-old woman presented with abdominal distension for 1 week. Abdominal contrast-enhanced CT showed 2 abnormal enhanced lesions in uterine fundus and in the lower pole of the right kidney, suggesting a probability of malignancies. As part of a clinical trial, the patient underwent both 18 F-FAPI and 18 F-FDG PET/CT to assess the malignancy of the lesions. Compared with 18 F-FDG PET/CT, 18 F-FAPI PET/CT demonstrated more intense and extensive tracer uptake in these lesions. Finally, pathologic analysis confirmed perivascular epithelioid cell tumors.
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Yan et al. (2025) studied this question.
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