A new entity of abdominal squamous cell carcinoma of unknown primary

Patients diagnosed with cancer of unknown primary (CUP) present a clinicopathologic syndrome defined by the presence of histologically metastatic cancer without an identifiable primary tumor after a complete work-up [1]. CUP accounts for 3-5% of all invasive cancers which accounts for the seventh to eight most common malignancy [2]. It ranks as the fourth most common cause of cancer deaths and represents both a diagnostic and a management challenge [2]. This article is protected by copyright. All rights reserved.