Chemical-shift changes in samples containing the proton donors CF3CH2OH and C6F5OH and a nitroxide free radical have been measured. The values of the association constants for the donor:radical complexes determined from them are smaller than those measured by observing the changes in hyperfine coupling constants in the EPR spectrum of the same radical:donor systems because the chemical-shift measurements are sensitive to all interactions between the radical and donor solvent molecule nuclei, not just those arising from the formation of the transient hydrogen-bonded complex.
No takes yet. Share an insight, caveat, or question.
Bonesteel et al. (1992) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: