Median age of menarche was determined in children of European and Aymara ancestry residing in La Paz, Bolivia (3600 m) and in children of European ancestry residing in Santa Cruz, Bolivia (400 m). Median age of menarche in European and Aymara highland natives was younger than reported by previous researchers, thus broadening the range of variation in age of menarche in high-altitude populations. Comparisons between La Paz and Santa Cruz European children suggested that growth and development at high altitudes results in a delay in median age of menarche of about 0.8 years.
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Lawrence P. Greksa (1990) studied this question.
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