Key result
Asymptomatic hypertrophic cardiomyopathy presents as sudden cardiac death at 28 weeks' gestation.
Why the study?
The pathophysiological mechanisms and clinical implications of sudden death during pregnancy in hypertrophic cardiomyopathy are not well understood.
Key points are not available for this paper at this time.
Population
A 27-year-old pregnant woman with hypertrophic cardiomyopathy
Design
Case report
Highlights possible sudden death risk in pregnant HCM patients; single case leaves open need for systematic risk assessment.
A 27-year-old asymptomatic woman became pregnant 6 months after a diagnosis of hypertrophic cardiomyopathy and was well until 28 weeks' gestation when she died suddenly while running up stairs. The potential pathophysiological mechanisms of sudden death during pregnancy in hypertrophic cardiomyopathy, as well as the diagnostic and therapeutic implications, are discussed.
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Pelliccia et al. (1992) studied this question. Hypertrophic cardiomyopathy in a previously asymptomatic 27-year-old pregnant woman resulted in sudden death at 28 weeks' gestation.
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