Key result
Regular endurance exercise is linked to adverse cardiometabolic risk factor responses in ~7% of adults.
Why the study?
The pathological causes of sudden death during athletics vary by age, and cardiovascular screening programs face limitations in reducing exercise-related deaths.
Observational (n=1,687)
Yes
May warrant monitoring select cardiometabolic markers during endurance training; leaves open identification of adverse responders in prospective studies.
The pathological causes of sudden death during athletics varies with the age of the competitor. Congenital abnormalities are the predominant cause of exercise-related deaths in subjects under age 30 yr whereas atherosclerotic coronary artery disease is the primary cause of such deaths in adults. Cardiovascular screening programs designed to reduce the incidence of exercise deaths are limited by the rarity of exercise events, the poor predictive value of the tests, and the cost of testing. Nevertheless, we recommend that young athletes be examined to detect conditions associated with exercise complications and that new symptoms in young and old athletes be carefully evaluated.
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A 1993 study conducted an observational in Sedentary adults (n=1,687). Regular endurance exercise vs. Baseline was evaluated on Prevalence of adverse response in at least two cardiometabolic risk factors (fasting insulin, HDL-C, triglycerides, or systolic blood pressure). Regular endurance exercise resulted in adverse responses for at least two common cardiometabolic risk factors in approximately 7% of sedentary adults, independent of improvements in cardiorespiratory fitness.
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