Key result
The GRACE risk score significantly predicted 30-day cardiovascular death in STEMI patients (OR 1.43 per 10-point increase) and demonstrated high discriminatory accuracy that was further improved by adjusting for interventional treatment and chronic atrial fibrillation.
Why the study?
The study aimed to evaluate the informative value of GRACE risk score models and identify additional indicators for short-term and long-term prognosis in ACS patients.
Cohort (n=1,491)
No
Odds Ratio: 1.43 (95% CI 1.27–1.62)
Ischemic heart disease is the leading cause of death in Europe among males over 45 years of age and females older than 65. The aim of the study: to evaluate the informative value of the models in ACS patients using GRACE (GR) risk score, to identify additional informative indicators for short-term and long-term prognosis following ACS, and to evaluate the prognostic reliability of the integrated model. The study included 1491 patients who in 2005 were treated for ACS in the Department of Cardiology, the Hospital of Kaunas University of Medicine. We devised an adjusted prognostic index for making short and long-term prognosis in patients with acute coronary syndromes (STEMI and NSETMI). Following adjustment of the GR scores, the prognostic value improved for STEMI patients. Ill. 2, bibl. 12, tabl. 3 (in English; abstracts in English and Lithuanian).http://dx.doi.org/10.5755/j01.eee.110.4.292
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Babarskienė et al. (2011) conducted a cohort in Acute Coronary Syndromes (STEMI and NSTEMI) (n=1,491). GRACE risk score vs. Lower GRACE risk score was evaluated on 30-day cardiovascular death risk per 10-point increase in GRACE score (STEMI patients) (OR 1.43, 95% CI 1.27-1.62). The GRACE risk score significantly predicted 30-day cardiovascular death in STEMI patients (OR 1.43 per 10-point increase) and demonstrated high discriminatory accuracy that was further improved by adjusting for interventional treatment and chronic atrial fibrillation.
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