A palladium-mediated domino reaction was developed to conveniently synthesize phenanthridinone derivatives. Phosphine ligand 1 strongly promotes the domino process, which includes aryl-aryl coupling and C-N bond formations concomitant with a deamidation reaction. The versatility and applicability to a broad range of substrates make this reaction useful for the development of bioactive derivatives. [reaction: see text].
No takes yet. Share an insight, caveat, or question.
Furuta et al. (2006) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: