Key result
Surgical resection with immunosuppression achieves clinical remission in right atrial myxoma with GPA.
Why the study?
Granulomatosis with polyangiitis and cardiac myxomas are rare conditions that can co-exist, but no prior case report has described a patient with GPA and a confirmed myxoma.
Case Report (n=1)
No
May support myxoma resection plus immunosuppression in rare GPA cardiac involvement; leaves open generalizability and requires prospective validation.
BACKGROUND: Granulomatosis with polyangiitis and myxomas are rare conditions previously described to co-exist. Cardiac masses are often presumed to be myxomas rather than lesions of granulomatosis with polyangiitis. CASE PRESENTATION: We present a review of the symptoms for the two diagnoses along with the first verified case. CONCLUSIONS: Two possible risk factors for developing myxomas (VEGF and IL-6) are explored and discussed.
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Björn Peters (2022) conducted a case report in Granulomatosis with polyangiitis and right atrial myxoma (n=1). Surgical extirpation and immunosuppressive therapy was evaluated on Clinical remission and resolution of symptoms. Surgical extirpation of a right atrial myxoma combined with immunosuppressive therapy successfully achieved clinical remission in a 58-year-old woman with granulomatosis with polyangiitis.
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