Purpose Supply chains for pathogen genomic sequencing (PGS) materials in sub-Saharan Africa face numerous noteworthy challenges that have received limited attention in research. This paper aims to highlight the most salient challenges from the perspective of key stakeholders in the supply chain and proposes a path toward sustainable solutions. Design/methodology/approach Using a qualitative approach, the authors conducted 54 extensive semi-structured interviews with stakeholders along the supply chain and used data analysis to highlight the key challenges. The authors then drew upon the literature and our analysis and experience to develop a set of design propositions for Communities of Practice (CoP) as locally-owned structures for knowledge sharing and learning on supply chain management (SCM) practices. Findings The authors identify nine categories of challenges, including long and unpredictable lead times, need for cold chain infrastructure and uncertain future funding. The authors also find evidence that stakeholders have siloed views of challenges which limits their ability to conceptualize sustainable solutions with long-term impact. Significant variability in the maturity of SCM practices between laboratories suggests the usefulness of a cross-organizational learning approach amongst laboratories, motivating the development of CoP. Originality/value PGS capacity in sub-Saharan Africa is at an early stage of development with multiple initiatives that are seeking to establish broad, equitable access. This paper provides a way forward for such initiatives by taking a comprehensive view of these supply chains and defining a number of design propositions for establishing CoP. The authors argue that improving labs’ SCM capabilities could have positive spillovers for the entire supply chain.
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Bam et al. (2026) studied this question.
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