Key result
ECG V1R amplitude identifies right ventricular dilation with ~77% specificity in repaired tetralogy of Fallot.
Why the study?
Cardiac MRI is crucial for timing pulmonary valve replacement in repaired tetralogy of Fallot patients but its availability is limited, necessitating alternative predictive tools.
Do specific ECG indicators (such as V1R) predict right ventricular dilation on cardiac MRI in patients with repaired tetralogy of Fallot?
Observational (n=35)
Do specific ECG indicators (such as V1R) predict right ventricular dilation on cardiac MRI in patients with repaired tetralogy of Fallot?
V1R amplitude on ECG demonstrates moderate sensitivity and specificity for predicting right ventricular dilation on MRI, suggesting it can aid in screening and timing of pulmonary valve replacement for rTOF patients.
V1R amplitude may support ECG screening for RV dilation in repaired tetralogy of Fallot; leaves open prospective validation before influencing pulmonary valve replacement timing.
BACKGROUND: Patients with surgically repaired tetralogy of Fallot (rTOF) often develop chronic pulmonary regurgitation (PR), necessitating pulmonary valve replacement (PVR). While cardiac MRI is crucial for PVR timing, its availability is limited. This study evaluates electrocardiographic (ECG) findings - specifically the R-wave amplitude in lead V1 (V1R) and the sum of the R-wave amplitude in lead V1 and the deepest S-wave amplitude in lead V5 or V6 (V1R + V5S or V6S) - as predictors of cardiac MRI findings. PATIENTS AND METHODS: We retrospectively analyzed 35 rTOF patients (mean age 34 ± 9 years; 60% male) who underwent cardiac MRI from 2019 to 2022, assessing correlations between ECG parameters (V1R, V1R + V5S or V6S, and QRS duration) and MRI findings (RVESVI and RVEDVI). RESULTS: with 67% sensitivity and 77% specificity. CONCLUSIONS: V1R on ECG may help predict the need for cardiac MRI, aiding in the timely PVR planning for rTOF patients.
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Hiya et al. (2025) conducted an observational in surgically repaired tetralogy of Fallot (rTOF) (n=35). Electrocardiographic findings (V1R and V1R + V5S or V6S) was evaluated on Prediction of cardiac MRI findings (RVESVI and RVEDVI). Electrocardiographic V1R amplitude predicted cardiac MRI findings with 67% sensitivity and 77% specificity in patients with surgically repaired tetralogy of Fallot.
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