Angiograms of proved malignant neoplasms were evaluated to identify criteria of malignancy and to compare their incidence with nonmalignant controls. Three angiographers studied the material, which was then analyzed by a shared-time computer, and a strategy was developed for evaluating the data. This double-blind study revealed that perivascular cuffing (encasement) was the most reliable criterion; in its absence, neovascularity and associated arterial and venous occlusion and deformity were of equal importance. The absence of neovascularity strongly suggests benignancy.
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Ney et al. (1972) studied this question.
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