Key result
Detailed transseptal PFO closure yields 100% procedural success with minimal residual shunts and no new-onset AF.
Why the study?
The closure of a patent foramen ovale using transseptal puncture has particular advantages and disadvantages that require detailed re-evaluation.
Does the detailed transseptal PFO closure technique reduce residual shunts and atrial fibrillation in patients with a long-tunnel PFO?
Cohort (n=144)
Yes
Does the detailed transseptal PFO closure technique reduce residual shunts and atrial fibrillation in patients with a long-tunnel PFO?
The detailed transseptal technique for PFO closure in long-tunnel anatomies may offer a safe approach with low rates of residual shunts and procedural complications.
Background: The closure of a patent foramen ovale (PFO) using transseptal puncture has particular advantages and disadvantages. Thus, transseptal puncture should be re-evaluated in detail. Aims: We aimed to assess the effectiveness of the detailed transseptal puncture technique in patients who underwent PFO closure due to cryptogenic stroke or transient ischemic attack in terms of residual shunts and atrial fibrillation. Methods: We prospectively analyzed 144 consecutive patients who underwent PFO closure by the detailed transseptal puncture technique between February 2013 and April 2023 in two centers. All of the patients had a >10 mm long-tunnel PFO. Results: The procedural success rate was 100%. However, after the procedure, moderate pericardial effusion developed in one patient (0.7%) and an acute pulmonary embolism related to femoral vein thrombosis was observed in one patient (0.7%) during the first month. Complications related to the procedure were noted in two patients (1.4%) during the first month of follow-up. Residual shunts were observed in 1.4% of cases after PFO closure. Conclusion: We demonstrated that the detailed transseptal technique is safe and effective for PFO closure. The detailed transseptal PFO closure technique significantly reduced the risk of atrial fibrillation, and the occurrence of residual shunts was significantly low following the closure.
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İlkay et al. (2024) conducted a cohort in Patent foramen ovale (PFO) with cryptogenic stroke or TIA (n=144). Detailed transseptal PFO closure technique was evaluated on Residual shunt rate at follow-up. The detailed transseptal PFO closure technique achieved a 100% procedural success rate, with residual shunts occurring in only 1.4% of patients and no documented cases of new-onset atrial fibrillation.
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