A clinical dilemma for treatment choice of extramedullary spinal plasmacytoma in patients with multiple myeloma: chemotherapy or surgery? A double-case clinical report

Two presented case reports that highlight extramedullary spinal cord plasmacytomas in patients with diagnosed multiple myeloma are intended to change the paradigm of understanding the indication of surgical intervention. In the first case, the condition manifested as a relapse of kappa light chain multiple myeloma, whereas in the second case, it emerged as a primary manifestation of the same disease. Both patients received a combination chemotherapy of bortezomib, lenalidomide, and dexamethasone, which proved to be highly effective, eliminating the need for surgical intervention.