I have always been fascinated by the mechanisms by which viruses, and other microorganisms, bypass and/or cross cellular barriers to enter their human hosts.As a trainee and young investigator, my research primarily focused on how enteroviruses cross the barriers presented by the epithelium and endothelium.Yet, despite all my years focused on cellular barriers, there was a barrier I had always overlooked, until faced with the stark reality of its importance-the placenta, which forms the barrier between mother and her developing baby during pregnancy.Early in my pregnancy, as I sat prepping large volumes of highly infectious enteroviruses, a question suddenly occurred to me: "What is protecting my baby from these viruses?"A quick Image 1.
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Carolyn B. Coyne (2016) studied this question.
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