Functional role of the 503F variant of the organic cation transporter OCTN1 in Crohn’s disease: Figure 1

We are grateful to Such et al for their comments on our review.As we had outlined, the influence of bacterial infection on the pathophysiology of cirrhosis is indeed an important one and Such et al have contributed significantly to this topic.[1][2][3][4] We were aware of their data, but unfortunately some of it could not be retained in the final version of our paper due to editorial restrictions.Nevertheless, we agree that the presence of bacterial DNA, in the absence of viable bacteria or endotoxaemia, might be an additional step in the sequence of events outlined in fig 2 of our review, maybe even preliminary to endotoxaemia.