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BACKGROUND: The marine environment has shown to be an interesting source of new antitumor agents, representing an important tool in cancer research. OBJECTIVE: model of human colorectal cancer (Caco-2 cells). MATERIALS AND METHODS: The antitumor potential was accessed by evaluating Caco-2 cell's viability and proliferation through the 3-[4, 5-dimethylthiazol-2-yl]-2, 5-diphenyl tetrazolium bromide and calcein-AM methods. RESULTS: of 21.3 and 36.5 μg/mL, respectively. CONCLUSION: are promising sources of new bioactive molecules with application in cancer therapeutics. SUMMARY: MTT: 3-[4, 5-dimethylthiazol-2-yl]-2, 5-diphenyl tetrazolium bromide; DMSO: Dimethyl sulfoxide; FBS: Fetal bovine serum; MEM: Minimum Essential Medium; SEM: Standard error of the mean;SP : Sulfated polysaccharides.
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Alves et al. (2018) studied this question.