A Study of 39 Cases of Primary Hyperparathyroidism

This is the authors' abstract. We don't add key points for this paper.

Primary hyperparathyroidism (PHPT) is a disorder characterized by hypercalcemia, with an increasing prevalence of asymptomatic cases. Surgical excision of the pathological gland is the definitive treatment, and accurate preoperative localization is essential. We analyzed the data of 39 patients with PHPT who underwent surgery. Of the 39 patients, 72.5% were asymptomatic. While ultrasonography alone had limited diagnostic accuracy, combined ultrasonography plus MIBI scintigraphy or CT improved the localization in all cases. Some postoperative cases showed discrepancies between the serum calcium and i-PTH levels. Even in asymptomatic cases, the surgical indication should be based on a comprehensive assessment, and it cannot be overemphasized that the procedures must be performed safely and appropriately.