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(1) This study indicated that both GK-101 and GK-101E exerted a statistically significant chemical action in the removal of carious material, in addition to any mechanical effects of the delivery system and applicator tip. (2) The superiority of GK-101E over saline in caries removal was noted, regardless of lesion consistency. (3) GK-101 was statistically superior to saline in caries removal in medium-hard lesions; it was not statistically superior to saline in lesions of medium consistency.
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Schutzrank et al. (1978) studied this question.
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