Granular cell tumor is an uncommon soft-tissue tumor that is usually benign and readily treated with complete resection. Malignant granular cell tumors are perhaps the rarest of all soft-tissue tumors, and they commonly metastasize to regional lymph nodes and the lungs. We present a case of granular cell tumor that exhibited both gross and microscopic features suggestive of malignancy without evidence of metastasis through a relatively short 16 months of follow-up and review the literature pertaining to granular cell tumors of uncertain malignant potential.
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Menaker et al. (1997) studied this question.
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