We describe a 65-year-old man who had medically refractory craniofacial dystonia with blepharospasm (Meige syndrome) and spasmodic torticollis (video, part 1). Initial botulinum toxin injections had been discontinued because of adverse side effects and a loss of efficacy. After informed consent, the patient received bilateral pallidal electrodes for deep brain stimulation (DBS). With neurostimulation, symptoms nearly resolved (video, part 2), with sustained efficacy at 4-month follow-up. Our case is in line with the few anecdotal descriptions of treatment for Meige syndrome with pallidal DBS. 1,2 Our case demonstrates the efficacy of bilateral pallidal DBS for Meige syndrome and spasmodic torticollis.
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Opherk et al. (2006) studied this question.
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